This dosing option is only suitable for anal sex, not vaginal or frontal sex.
If you intend to use this regimen, then we advise that you take a daily dose for the first 7 days before switching to T’s and S’s and dropping down to 4 pills per week.
4 pills per week usually involves taking a pill on Tuesday, Thursday, Saturday and Sunday — that’s why it’s called ‘the Ts and Ss’.
This option has several benefits:
- If you only have sex once or twice a month, you might not want to take a pill every day. You might feel it’s more pills than you need to protect you for these 1 or 2 events.
- 4 pills per week will maintain a good baseline of drug in your system and you can choose to move up to 7 pills per week when you know you’re in a more sexually active period.
- Some people using PrEP On Demand find that they might be taking 4 pills per week most weeks of the month and so opt for structuring this into the Ts and Ss instead.
- If you are paying for your PrEP, it costs you less because it reduces the number of pills you take each month by almost half — which reduces the cost per month by almost half too.
Though these dosing options don’t seem to follow a simple rule, they are based on study data.